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Annali di Stomatologia | 2025; 16(4): 355-356

ISSN 1971-1441 | DOI: 10.59987/ads/2025.4.355-356

Editorial

Present and future of nickel-titanium in endodontics

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In recent decades, novel materials and techniques have been proposed to enhance the quality and outcomes of endodontic procedures. Among these innovations, nickel-titanium (NiTi) alloys have transformed endodontic instrumentation by combining superelasticity, shape-memory behavior, and biocompatibility, which together enable safer shaping of curved canals and shorter procedures compared with stainless-steel files (3,8,11). Yet important limitations persist: instrument separation driven by cyclic fatigue or torsional overload, variability of performance in real clinical conditions, and the perennial need to balance cutting efficiency, safety, and durability (5,9).

Much of the most substantial progress concerns the refinement of alloy processing, cross-sectional geometry, mass distribution, and kinematics. Experimental and clinical research—spanning imaging, canal morphology, and in vivo torque/temperature monitoring—has been pivotal for understanding how instruments actually perform and fail under realistic loads, thereby informing safer and more effective designs (111).

Current evidence converges on several points.

Future Directions: Challenges & Promising Trends

Based on the current evidence, some of the future directions and requirements include:

  1. Optimizing geometric designs for both fatigue resistance and cutting efficiency is essential. Innovative designs and reduced metal mass (including the absence of a core) may enhance fatigue life; however, they might adversely impact cutting performance, debris removal, or torsional strength. Future designs must therefore carefully balance these considerations. Additionally, a more precise assessment of cutting efficiency and debris removal will be required (3,4).
  2. Enhanced thermal and metallurgical control, coupled with a better understanding of phase transformations (austenite/martensite), heat treatments, and potentially new alloying or processing methods (such as cryogenic or innovative surface treatments), will persist in advancing fatigue life, strength, flexibility, and safety (11).
  3. Functionalized surfaces and coatings in nanoengineering have garnered significant attention. To date, most research has focused on geometry, design, and torque/fatigue. However, the broader field also encompasses surface functionalization, including coatings and modifications aimed at reducing friction, wear, and microcracks. These represent promising areas for future development (8).
  4. Improved in vitro–in vivo correlation and the introduction of new metrics, such as the torque range, provide more clinically relevant parameters than static torsional failure. The integration of in vivo measurements—including torque, temperature, and usage cycles—with in vitro testing will facilitate the development and evaluation of instruments under more realistic stress conditions (5,6,9).
  5. Instrumentation, kinematics, and motion—reciprocation, adaptive motions, and novel motion protocols—may enhance fatigue resistance or ensure safer operation. The development of new motors and classification systems contributes by providing clearer comparative data (5).
  6. Single-file systems raise concerns regarding cost and reusability. As these systems gain popularity, it becomes essential to evaluate how reuse and sterilization procedures impact their strength, ensuring safety and cost-effectiveness (1,3).
  7. Regulatory Standards and Testing Protocols

There remains variability in the measurement of fatigue, torsional stress, torsion under bending, and related factors. Numerous publications emphasize the importance of standardizing test canals, artificial curvature, temperature control, and failure endpoints. Achieving future consensus on testing protocols will facilitate more effective comparisons across studies and assist manufacturers in aligning with reproducible safety standards (9,11).

Conclusion

In summary, Nickel-Titanium continues to be the primary material for contemporary endodontic canal shaping, owing to its flexibility, strength, and ability to mitigate procedural risks. Recent scholarly contributions have substantially enhanced the understanding of how design elements (such as geometry and cross-section), usage conditions (including new versus used instruments), operational parameters (such as torque and motion), and thermal treatments collectively influence performance and safety. Advancements in areas such as surface functionalization, innovative kinematic techniques, and the development of more realistic testing metrics are anticipated to further elevate the reliability, durability, and clinical safety of NiTi instruments.

References

  • 1. Cui C, Quan J, Wei X. Research progress in problem-solving nickel-titanium rotary instruments in endodontics. Hua Xi Kou Qiang Yi Xue Za Zhi. 2024 Dec 1;42(6):699–705. English, Chinese. doi:10.7518/hxkq.2024.2024225. PMID:39610066; PMCID:PMC11669929.
  • 2. Di Nardo D, Gambarini G, Capuani S, Testarelli L. Nuclear Magnetic Resonance Imaging in Endodontics: A Review. J Endod. 2018 Apr;44(4):536–542. doi:10.1016/j.joen.2018.01.001. Epub 2018 Feb 14. PMID:29426642.
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  • 4. Gambarini G. Shaping and cleaning the root canal system: a scanning electron microscopic evaluation of a new instrumentation and irrigation technique. J Endod. 1999 Dec;25(12):800–803. doi:10.1016/S0099-2399(99)80300-8. PMID:10726524.
  • 5. Gambarini G, Piasecki L, Miccoli G, Gaimari G, Di Giorgio R, Di Nardo D, Azim AA, Testarelli L. Classification and cyclic fatigue evaluation of new kinematics for endodontic instruments. Aust Endod J. 2019 Aug;45(2):154–162. doi:10.1111/aej.12294. Epub 2018 Aug 16. PMID:30113735.
  • 6. Gambarini G, Seracchiani M, Piasecki L, Valenti Obino F, Galli M, Di Nardo D, Testarelli L. Measurement of torque generated during intracanal instrumentation in vivo. Int Endod J. 2019 May;52(5):737–745. doi:10.1111/iej.13042. Epub 2018 Dec 4. PMID:30444531.
  • 7. Mashyakhy M, Gambarini G. Root and root canal morphology differences between genders: a comprehensive in vivo CBCT study in a Saudi population. Acta Stomatol Croat. 2019 Sep;53(3):213–246. doi:10.15644/asc53/3/5. PMID:31749454; PMCID:PMC6820446.
  • 8. Ounsi HF, Nassif W, Grandini S, Salameh Z, Neelakantan P, Anil S. Evolution of nickel-titanium alloys in endodontics. J Contemp Dent Pract. 2017 Nov 1;18(11):1090–1096. doi:10.5005/jp-journals-10024-2181. PMID:29109327.
  • 9. Plotino G, Grande NM, Mazza C, Petrovic R, Testarelli L, Gambarini G. Influence of size and taper of artificial canals on the trajectory of NiTi rotary instruments in cyclic fatigue studies. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan;109(1):e60–e66. doi:10.1016/j.tripleo.2009.08.009. Epub 2009 Nov 17. PMID:19926504.
  • 10. Setzer FC, Li J, Khan AA. The use of artificial intelligence in endodontics. J Dent Res. 2024 Aug;103(9):853–862. doi:10.1177/00220345241255593. Epub 2024 May 31. PMID:38822561; PMCID:PMC11378448.
  • 11. Zupanc J, Vahdat-Pajouh N, Schäfer E. New thermomechanically treated NiTi alloys—a review. Int Endod J. 2018 Oct;51(10):1088–1103. doi:10.1111/iej.12924. Epub 2018 Apr 19. PMID:29574784.