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Annali di Stomatologia | 2026; 17(3): 3 ISSN 1971-1441 | DOI: 10.59987/ads/2026.3 Editorial |
The Future of Endodontics. Will Dentists Save More Teeth in the Next Decades?
For decades, endodontics has been at the forefront of preserving natural teeth, transforming what was once considered a hopeless diagnosis into a treatable condition [1]. As dentistry continues to embrace technological innovation and biological discoveries [2–3], the future of endodontics appears brighter than ever. Rather than relying solely on conventional root canal therapy, tomorrow’s clinicians will increasingly combine advanced diagnostics, regenerative techniques, and minimally invasive procedures [1–2,4] to preserve teeth that might otherwise have been extracted. The central question is no longer whether endodontics will evolve, but how significantly it will improve the long-term survival of natural dentition [5].
Several emerging technologies are already reshaping clinical practice. Three-dimensional imaging [2,6–9], artificial intelligence-assisted diagnosis, operating microscopes, and advanced nickel-titanium instrumentation [10–13] have dramatically improved the precision and predictability of root canal treatment [14–20]. Modern bioceramic materials provide superior sealing ability and promote healing, while digital workflows enhance treatment planning and patient communication [4]. These innovations reduce procedural errors, improve outcomes, and make complex cases more manageable [1]. As these technologies become more accessible and affordable, dentists will be better equipped to save teeth that previously had a poor prognosis.
Research will play a decisive role in determining the future of endodontics. Besides traditional ex vivo research evaluating products for cleaning, shaping, and obturating root canals [10–14,17–20], ongoing investigations into regenerative endodontics, stem cell biology, tissue engineering, and biomimetic materials are opening the possibility of restoring the vitality of damaged pulp rather than simply removing it [1]. Clinical research also continues to refine irrigation protocols and antimicrobial strategies [21–22], and restorative techniques that enhance the longevity of treated teeth [5]. Equally important, evidence-based dentistry ensures that new technologies are adopted only after rigorous scientific evaluation, providing patients with treatments that are both innovative and proven to be safe and effective [1]. Continued investment in multidisciplinary research will therefore be essential for translating laboratory discoveries into everyday clinical practice.
Despite these remarkable advances, challenges remain. The increasing prevalence of aging populations, complex restorations, dental trauma, and systemic diseases will continue to test the limits of endodontic care. Furthermore, successful tooth preservation depends not only on excellent endodontic treatment but also on accurate diagnosis, periodontal health, timely restoration, and patient commitment to oral hygiene [1,5]. Education, prevention, and interdisciplinary collaboration between general dentists, endodontists, prosthodontists, and periodontists will remain fundamental to achieving long-term success. Universities are also currently improving their facilities and methods for teaching pre-clinical endodontics, using new simulators and more sophisticated materials to mimic the clinical experience and allow students to start practicing on patients after proper initial training.
The future of endodontics is ultimately a future centered on preserving the natural dentition whenever possible [1,5]. As scientific knowledge expands and technology continues to advance, dentists are likely to save more teeth than ever before, improving both oral health and patients’ quality of life. While dental implants will remain an important treatment option, the preservation of natural teeth will continue to be the gold standard [1,5]. The coming decades promise a shift from simply treating disease to biologically restoring dental tissues, ensuring that more patients can retain their own teeth for a lifetime.
References
- 1. Duncan HF, Kirkevang LL, Peters OA, El-Karim I, Krastl G, Del Fabbro M, et al. Treatment of pulpal and apical disease: the European Society of Endodontology (ESE) S3-level clinical practice guideline. Int Endod J. 2023;56 Suppl 3:238–295. doi:10.1111/iej.13974.
- 2. Di Nardo D, Gambarini G, Capuani S, Testarelli L. Nuclear magnetic resonance imaging in endodontics: a review. J Endod. 2018;44(4):536–542. doi:10.1016/j.joen.2018.01.001.
- 3. Lupi A, Messana I, Denotti G, Schininà ME, Gambarini G, Fadda MB, et al. Identification of the human salivary cystatin complex by the coupling of high-performance liquid chromatography and ion-trap mass spectrometry. Proteomics. 2003;3(4):461–467. doi:10.1002/pmic.200390060.
- 4. Gambarini G, Galli M, Morese A, Stefanelli LV, Abduljabbar F, Giovarruscio M, et al. Precision of dynamic navigation to perform endodontic ultraconservative access cavities: a preliminary in vitro analysis. J Endod. 2020;46(9):1286–1290. doi:10.1016/j.joen.2020.05.022.
- 5. Mannocci F, Bhuva B, Roig M, Zarow M, Bitter K. European Society of Endodontology position statement: the restoration of root-filled teeth. Int Endod J. 2021;54(11):1974–1981. doi:10.1111/iej.13607.
- 6. Capuani S, Gambarini G, Guarnieri R, Di Pietro G, Testarelli L, Di Nardo D. Nuclear magnetic resonance microimaging for the qualitative assessment of root canal treatment: an ex vivo preliminary study. Diagnostics (Basel). 2021;11(6):1012. doi:10.3390/diagnostics11061012.
- 7. Mashyakhy M, Gambarini G. Root and root canal morphology differences between genders: a comprehensive in vivo CBCT study in a Saudi population. Acta Stomatol Croat. 2019;53(3):213–246. doi:10.15644/asc53/3/5.
- 8. Valenti-Obino F, Di Nardo D, Quero L, Miccoli G, Gambarini G, Testarelli L, et al. Symmetry of root and root canal morphology of mandibular incisors: a cone-beam computed tomography study in vivo. J Clin Exp Dent. 2019;11(6):e527–e533. doi:10.4317/jced.55629.
- 9. Reda R, Zanza A, Cicconetti A, Bhandi S, Miccoli G, Gambarini G, et al. Ultrasound imaging in dentistry: a literature overview. J Imaging. 2021;7(11):238. doi:10.3390/jimaging7110238.
- 10. Bago I, Vidovic I, Testarelli L, Galli M, Milanovic-Litre M, Katic M, et al. Percentage of root canal wall surfaces touched by rotary nickel-titanium instruments: a systematic review and a preliminary experimental evaluation of a new instrument. Annali Di Stomatologia. 2026;17(2):406–416. doi:10.59987/ads/2026.2.406-416.
- 11. Wanga L, Zhang J, Li W, Yang Z. An in vitro study of the ability of three new continuous rotary heat-treated nickel-titanium files to shape curved root canals. Annali Di Stomatologia. 2025;16(1):3–9. doi:10.59987/ads/2025.1.3-9.
- 12. Feghali M, Gambarini G, Grande NM, Di Nardo D, Galli M. Comparative ex vivo evaluation of mechanical properties of three orifice openers. Annali Di Stomatologia. 2026;17(2):242–249. doi:10.59987/ads/2026.2.242-249.
- 13. Gambarini G. Shaping and cleaning the root canal system: a scanning electron microscopic evaluation of a new instrumentation and irrigation technique. J Endod. 1999;25(12):800–803. doi:10.1016/S0099-2399(99)80300-8.
- 14. Giansiracusa Rubini A, Plotino G, Al-Sudani D, Grande NM, Sonnino G, Putorti E, et al. A new device to test cutting efficiency of mechanical endodontic instruments. Med Sci Monit. 2014;20:374–378. doi:10.12659/MSM.890119.
- 15. Gambarini G, Seracchiani M, Piasecki L, Valenti Obino F, Galli M, Di Nardo D, et al. Measurement of torque generated during intracanal instrumentation in vivo. Int Endod J. 2019;52(5):737–745. doi:10.1111/iej.13042.
- 16. Signorini L, Vincenzi V, Bago I, Vidovic I, Federici FR, Galli M, et al. A comparison between clinical operative torque and in vitro torsional resistance. Annali Di Stomatologia. 2025;16(4):371–374. doi:10.59987/ads/2025.4.371-374.
- 17. Gambarini G, Miccoli G, Seracchiani M, Khrenova T, Donfrancesco O, D’Angelo M, et al. Role of the flat-designed surface in improving the cyclic fatigue resistance of endodontic NiTi rotary instruments. Materials (Basel). 2019;12(16):2523. doi:10.3390/ma12162523.
- 18. Ovsay E, Atav A, AlOmari T, Bhardwaj A. Role of temperature on the cyclic fatigue resistance of thermally treated Ni-Ti files: cyclic fatigue and temperature. Annali Di Stomatologia. 2025;16(1):37–41. doi:10.59987/ads/2025.1.37-41.
- 19. Plotino G, Grande NM, Testarelli L, Gambarini G, Castagnola R, Rossetti A, et al. Cyclic fatigue of Reciproc and Reciproc Blue nickel-titanium reciprocating files at different environmental temperatures. J Endod. 2018;44(10):1549–1552. doi:10.1016/j.joen.2018.06.006.
- 20. Zanza A, Seracchiani M, Di Nardo D, Reda R, Gambarini G, Testarelli L. A paradigm shift for torsional stiffness of nickel-titanium rotary instruments: a finite element analysis. J Endod. 2021;47(7):1149–1156. doi:10.1016/j.joen.2021.04.017.
- 21. Bolla N, Cross R, Basam RC, Vemuri S, Bolla L, Chukka R. Chairside ATP assessment of root canal disinfection: a clinical evaluation of six irrigation protocols. Annali Di Stomatologia. 2025;16(3):221–233. doi:10.59987/ads/2025.3.221-233.
- 22. Plotino G, Grande NM, Mercade M, Cortese T, Staffoli S, Gambarini G, et al. Efficacy of sonic and ultrasonic irrigation devices in the removal of debris from canal irregularities in artificial root canals. J Appl Oral Sci. 2019;27:e20180045. doi:10.1590/1678-7757-2018-0045.
