Biocompatibility of a new pulp capping cement
Authors
C. Poggio , M. Ceci, R. Beltrami, A. Degna , M. Colombo , M. Chiesa
Abstract
VOLUME 5 - NUMBER 2 - 2014 Biocompatibility of a new pulp capping cement
- Poggio C., Ceci M., Beltrami R., Degna A., Colombo M., Chiesa M.
- Original Article, 69-75
- Full text PDF
Aim. The aim of the present study was to evaluate the biocompatibility of a new pulp capping material (Biodentine, Septodont) compared with reference pulp capping materials: Dycal (Dentsply), ProRoot MTA (Dentsply) and MTA-Angelus (Angelus) by using murine odontoblast cell line and Alamar blue and MTT cytotoxicity tests.
Methods. The citocompatibility of murine odontoblasts cells (MDPC-23) were evaluated at different times using a 24 Transwell culture plate by Alamar blue test and MTT assay.
Results. The results were significantly different among the pulp capping materials tested. Biocompatibility was significant different among materials with different composition.
Conclusions. Biodentine and MTA-based products show lower cytotoxicity varying from calcium hydroxide-based material which present higher citotoxicity.
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