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Vol. 16 No. 2 (2025)
DOI: 10.59987/ads/2025.2.70-74
Articles
2025-07-08

Managing patients with von willebrand disease in dentistry: a case report

Authors

Luciano Pacifici, Giulia Caporro, Domenico Gaglioti, Cristina Santoro, Gianluca Tenore, Andrea Pacifici

Keywords: Von Willebrand disease, Coagulation factor VIII, FVIII/VWF concentrate, Oral Surgery

Abstract

Aim: Von Willebrand disease (VWD) is the most common inherited coagulopathy, characterized by a quantitative or qualitative deficiency of Von Willebrand factor (VWF), essential for primary and secondary hemostasis. Patients with VWD have an increased risk of bleeding, which can complicate dental procedures. This case report aims to provide a comprehensive overview of the dental management of patients with VWD, outlining practical strategies and recommendations to address the specific clinical challenges of this condition in the field of oral surgery. Case report: A 42-year-old male patient with VWD type 1 presented to our Department for extraction of element 3.8 for dysodontiasis. Results: The surgical extraction was performed successfully. No intraoperative or postoperative issues were encountered. Conclusion: Effective communication and collaboration among the dentist, hematologist, and patient are essential to optimize prognosis by reducing the risks of intra- and postoperative complications.

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Authors

Luciano Pacifici - Department of Oral and Maxillofacial Sciences, “Sapienza” University of Rome.

Giulia Caporro - Department of Oral and Maxillofacial Sciences, “Sapienza” University of Rome.

Domenico Gaglioti - Department of Oral and Maxillofacial Sciences, “Sapienza” University of Rome.

Cristina Santoro - Department of Cellular Biotechnology and Hematology, "Sapienza" University of Rome

Gianluca Tenore - Department of Oral and Maxillofacial Sciences, “Sapienza” University of Rome.

Andrea Pacifici - Department of Oral and Maxillofacial Sciences, “Sapienza” University of Rome.

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Copyright (c) 2025 Luciano Pacifici, Giulia Caporro, Domenico Gaglioti, Cristina Santoro, Gianluca Tenore, Andrea Pacifici

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors contributing to Annali di Stomatologia agree to publish their articles under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows third parties to copy and redistribute the material providing appropriate credit and a link to the license but does not allow to use the material for commercial purposes and to use the material if it has been remixed, transformed or built upon.

How to Cite
Pacifici, L., Caporro, G., Gaglioti, D., Santoro, C., Tenore, G., & Pacifici, A. (2025). Managing patients with von willebrand disease in dentistry: a case report. Annali Di Stomatologia, 16(2). https://doi.org/10.59987/ads/2025.2.70-74

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