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Influence of irrigating solutions on the efficacy of new single-file reciprocation instruments

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Abstract

The aim of this clinical study is to evaluate the impact of two different irrigating solutions—2.5% NaOCl and Dual Rinse HEDP—on the effectiveness of the Direct-R Gold single-file reciprocating system during in vivo root canal treatment. The study was conducted at the Clinical Hospital Center Rijeka, Croatia, and treatments were performed by sixth-year dental students under specialist supervision at the Faculty of Dental Medicine, University of Rijeka. All patients provided informed consent. A total of 98 root canals were included and divided into two groups (n = 50) based on the irrigant used: 2.5% sodium hypochlorite (NaOCl) or Dual Rinse® HEDP (prepared by dissolving the HEDP capsule in 10 mL of 2.5% NaOCl). Instruments were used according to the manufacturer’s IFU. Students were asked to report canal difficulty and any signs of deformation or fracture, if present. Data were recorded in Excel and statistically analyzed using chi-square tests and multinomial logistic regression. Out of 98 treated root canals, Direct-R Gold achieved full working length in most cases, regardless of canal complexity or irrigant used. No significant links were found between apex reachability and irrigant type, case difficulty, or periapical status (p > 0.05). Therefore, we can conclude that Dual Rinse® HEDP neither improved nor impaired the instrument’s ability to reach the apex compared to sodium hypochlorite, and that Direct R Gold’s performance minimized the chances of detecting differences across these variables.

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Ivana Vidovic Zdrilic - University of Rijeka, Croatia

Ivana Brekalo Prso - University of Rijeka, Croatia

Romana Persic Bukmir - University of Rijeka, Croatia

Jelena Vidas Hrstić - University of Rijeka, Croatia

Alessio Zanza - University of Rome La Sapienza, Italy

Dario Di Nardo - University of Rome La Sapienza, Italy

Gianluca Gambarini - University of Rome La Sapienza, Italy

Ivona Bago - University of Zagreb, Croatia

How to Cite
Zdrilic, I. V. ., Prso, I. B. ., Persic Bukmir, R. ., Hrstić, J. V. ., Zanza, A., Di Nardo, D., Gambarini, G., & Bago, I. (2025). Influence of irrigating solutions on the efficacy of new single-file reciprocation instruments. Annali Di Stomatologia, 16(3), 302–307. https://doi.org/10.59987/ads/2025.3.302-307

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