Search

Surgery-first orthognathic approach: a narrative review of clinical rationale, comparative outcomes, digital workflow, and practical limits

Authors

Abstract

Orthognathic surgery remains the reference treatment for severe dentofacial deformities when orthodontic treatment alone cannot restore skeletal harmony, facial balance, and stable occlusal function. The surgery-first approach reverses the conventional orthodontics-first sequence by performing skeletal correction before comprehensive orthodontic decompensation, with the aim of reducing total treatment duration and providing immediate facial improvement. This narrative literature review synthesizes comparative evidence on treatment duration, skeletal stability, quality of life, digital workflow, practical limits, and patient selection. The evidence supports a clinically meaningful reduction in overall treatment time, generally without clear compromise of short- to medium-term stability in carefully selected cases. The strongest early advantages concern facial aesthetics, motivation, and oral health-related quality of life, whereas the main limitations involve occlusal instability, residual dentoalveolar compensation, relapse risk in complex patterns, and dependence on precise interdisciplinary planning. Keywords: orthognathic surgery; surgery-first approach; skeletal Class III malocclusion; dentofacial deformity; quality of life; cone-beam computed tomography; virtual surgical planning; regional acceleratory phenomenon.

Share on

Downloads

Authors

Lorenzo Silenzi Ederli - Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy https://orcid.org/0009-0004-6189-3137

Elisabetta Carli - Department of Surgical, Medical and Molecular Pathology and Critical Area, Dental Clinic, Uni-versity of Pisa, Pisa, Italy

Elvira Liotti - Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy

Mario Palermiti - Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy

Beatrice Marzo - Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy

Stefano Mummolo - Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy

How to Cite
Silenzi Ederli, L., Carli, E., Liotti, E., Palermiti, M., Marzo, B., & Mummolo, S. (2026). Surgery-first orthognathic approach: a narrative review of clinical rationale, comparative outcomes, digital workflow, and practical limits. Annali Di Stomatologia, 17(2), 450–457. https://doi.org/10.59987/ads/2026.2.450-457

Most read articles by the same author(s)